iReceptor Gateway user queries for Junction/CDR3 AA sequences in the AIRR Data Commons are now complemented with an additional search to IEDB to look for known antigen or epitope specificity. Organism found on IEDB with specificity are listed and the user is given a link to IEDB to find out more.
Check it out!
Excited to announce a sixth international repository in the AIRR Community AIRR Data Commons (ADC), now searchable through the iReceptor Gateway. Excited to collaborate with the Scheepers group at the HIV & SARS-CoV-2 Virology Section, National Institute for Communicable Diseases (NICD) in South Africa.
The iReceptor team recently presented at the Global COVID Lab Meeting of the Human Vaccines Project. "Antibody/B-cell and T-cell receptor sequences in the AIRR Data Commons promotes rapid response to COVID-19" was the topic of the day and the conversation following the excellent presentation was both thoughtful and thought-provoking. The presentation and discussion were recorded and can be found
We are pleased to announce a new AIRR-seq study available for searching and download in the AIRR Data Commons and through the iReceptor Gateway. 3.1M annotated sequences from Alameh et al. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses are now available through the iReceptor Gateway.
Due to a networking issue at the Texas Advanced Computing Centre (TACC) authentication of users on the iReceptor Gateway was not working from 15:00 PST to 16:00 PST. All services are now back online.
Interested in a list of relevant publications that have cited iReceptor and the AIRR Data Commons as a platform for sharing COVID-19 AIRR-seq data, check out this twitter thread by iReceptor Technical Director Brian Corrie describing the history of COVID-19 data sharing through third party publications and citations!
10X Genomics Canada presented a webinar entitled "Crucial Applications of Single Cell Gene Expression and Immune Profiling for Infectious Disease Research" on November 17th, 2021. Canadian researchers discussed the utility of single cell technologies to advance infectious disease research, highlighting how the scientific community can respond to such events.
We are pleased to announce the fourth COVID-19 AIRR-seq vaccine study (and eighteenth COVID-19 AIRR-seq study) available for searching and download in the AIRR Data Commons and through the iReceptor Gateway. 406K annotated sequences from Schmitz et al. A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants are now available through the iReceptor Gateway.
On October 8th, Felix Breden, iReceptor Scientific Director spoke at Chico State University Department of Biological Sciences about FAIR Data Curation of Antibody/B-cell and T-cell Receptor Sequences in the AIRR Data Commons promoting rapid response to COVID-19. The seminar introduced the faculty and students to the iReceptor Platform, the AIRR Data Commons, and how the culture of sharing these data for COVID-19 research has led to curation of over 1 Bn sequences from ~20 studies, including recent vaccine trials.