Our seventh T1D study has been added to the AIRR Data Commons, searchable through the iReceptor Gateway. 198K annotated T-cell receptors by Sally Kent et al. "Islet-derived, in vitro polyclonally expanded T cell Sequencing" from nPOD samples by the Kent Lab at the UMass Chan Diabetes Center of Excellence.
Our sixthT1D study has been added to the AIRR Data Commons, searchable through the iReceptor Gateway. 4.3 Million annotated T-cell receptors from Culina et al., "Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors" are now available.
Our fifth T1D study has been added to the AIRR Data Commons, searchable through the iReceptor Gateway. 32 Million annotated T-cell receptors from Gomez-Tourino et al., "T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes" are now available.
We had an excitiing 2023 in the iReceptor world, here is a summary of what happened in 2023, via X
The iReceptor Gateway Maintenance from 10:00 Jan 24 to 17:00 Jan 25 Pacific has been completed, please let support@ireceptor.org know if you see any problems.
Downtime: The iReceptor Gateway will be down from 10:00 Jan 24 to 17:00 Jan 25 Pacific Time for upgrades and maintenance. Apologies for the inconvenience.
The iReceptor team is excited to embark on a five year NIH/NIAID funded international project with colleagues from the University of Texas Southwestern Medical Center, the La Jolla Institute, the University of Louisville, and Cincinnati Children’s Hospital Medical Center as well as Bar-Ilan University in Israel, and Birkbeck College, University of London in England.
Our fourth T1D study has been added to the AIRR Data Commons, searchable through the iReceptor Gateway. Annotated T-cell receptors and subject HLA from Anderson et al. "Human islet T cells are highly reactive to preproinsulin in type 1 diabetes" is now available.
We are happy to announce a third Single Cell AIRRseq study available in the AIRR Data Commons. Rearrangement, Single Cell and Gene Expression data from Minervina et al. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells added to the AIRR Data Commons and searchable through the iReceptor Gateway.
We are happy to announce a second Single Cell AIRRseq study available in the AIRR Data Commons. Single Cell and Gene Expression data from Wen et al. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing added to the already existing bulk AIRR-seq study, searchable through the iReceptor Gateway.
